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Drug news Pivotal phase III trials of MK 8591 + Pifeltro meet endpoints in HIV. Merck Inc announced positive top-line results from two pivotal Phase III trials of the investigational, once-daily oral fixed dose combination pill of MK 8591 + Pifeltro (islatravir + doravirine) (DOR/ISL) in adults with HIV-1 infection who are virologically suppressed on different antiretroviral therapy regimens (ART; ILLUMINATE SWITCH A) or bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF; ILLUMINATE SWITCH B).
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Drug news Phase III TRYbeCA-1 trial of Graspa fails to meet primary endpoint in pancreatic cancer. ERYTECH Pharma announced top-line results from its Phase III TRYbeCA-1 clinical trial evaluating Graspa (eryaspase) as second-line treatment in 512 patients with metastatic pancreatic cancer.
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Drug news Retrospective chart review study of Variquel shows bleed control in esophageal variceal hemorrhage. Mallinckrodt announced results from a retrospective medical chart review study of Variquel (terlipressin) examining treatment patterns and outcomes in hospitalized patients with esophageal variceal hemorrhage (EVH) and liver cirrhosis treated with terlipressin.
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Drug news Pivotal phase III trials of MK 8591 + Pifeltro meet endpoints in HIV. Merck Inc announced positive top-line results from two pivotal Phase III trials of the investigational, once-daily oral fixed dose combination pill of MK 8591 + Pifeltro (islatravir + doravirine) (DOR/ISL) in adults with HIV-1 infection who are virologically suppressed on different antiretroviral therapy regimens (ART; ILLUMINATE SWITCH A) or bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF; ILLUMINATE SWITCH B).
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Drug news Phase III TRYbeCA-1 trial of Graspa fails to meet primary endpoint in pancreatic cancer. ERYTECH Pharma announced top-line results from its Phase III TRYbeCA-1 clinical trial evaluating Graspa (eryaspase) as second-line treatment in 512 patients with metastatic pancreatic cancer.
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Drug news Retrospective chart review study of Variquel shows bleed control in esophageal variceal hemorrhage. Mallinckrodt announced results from a retrospective medical chart review study of Variquel (terlipressin) examining treatment patterns and outcomes in hospitalized patients with esophageal variceal hemorrhage (EVH) and liver cirrhosis treated with terlipressin.
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